AIC-292

• UNSPSC Description:

  AIC-292 is a potent and selective inhibitor of HIV-1 nonnucleoside reverse transcriptase. AIC-292 inhibits wild-type HIV-1 laboratory strains at low nanomolar concentrations. AIC-292 displays potent antiviral in vivo efficacy in a mouse xenograft model. AIC-292 has the potential for the research of HIV-1 infection[1].

• Target Antigen:

  HIV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/aic-292.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1NCN(C(C2=NN(C3=CC=C(F)C(Cl)=C3)C(C4=CC(F)=CC(Cl)=C4)=C2)=O)C1

• Molecular Weight:

  437.23

• References & Citations:

  [1]Wildum S, et al. In vitro and in vivo activities of AIC292, a novel HIV-1 nonnucleoside reverse transcriptase inhibitor. Antimicrob Agents Chemother. 2013;57(11):5320-5329.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 1

• CAS Number:

  1187917-12-9