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Sulprostone

CAT: 0804-HY-19360Size: 1 mg (10.74 mM x 200 μL in Methyl Acetate)Dry Ice: NoHazardous: No
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CAT#:0804-HY-19360Size:1 mg (10.74 mM x 200 μL in Methyl Acetate)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sulprostone (SHB 286) is a potent and selective EP3 receptor agonist. Sulprostone (SHB 286) is a prostaglandin E2 (PGE2) analogue and has antiulcer and nonsteroidal abortifacient effects. Sulprostone has potential for the research of pregnancy termination and hemorrhages during delivery[1][2][3].
CAS Number
60325-46-4
Product Name Alternative
SHB 286; CP-34089; ZK-57671
UNSPSC
12352005
Hazard Statement
H315, H319, H335, H360
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sulprostone.html
Concentration
10.74 mM * 200 μL in Methyl acetate
Purity
99.0
Solubility
10 mM in DMSO
Smiles
O=C(NS(=O)(C)=O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)COC2=CC=CC=C2)[C@H](O)CC1=O
Molecular Formula
C23H31NO7S
Molecular Weight
465.56
Precautions
H315, H319, H335, H360
References & Citations
[1]S Narumiya, et al. Prostanoid receptors: structures, properties, and functions. Physiol Rev. 1999 Oct;79 (4) :1193-226.|[2]Jenny Bulgarelli, et al. Skewing effect of sulprostone on dendritic cell maturation compared with dinoprostone. Cytotherapy. 2018 Jun;20 (6) :851-860.|[3]Yifan Shi, et al. Bioanalysis of sulprostone, a prostaglandin E 2 analogue and selective EP 3 agonist, in monkey plasma by liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 15;1092:51-57.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EP

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