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GP3269

CAT: 0804-HY-19259Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19259Size:1 Each
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Description
GP3269 is a potent, selective, and orally active inhibitor of human adenosine kinase (AK) with an IC50 of 11 nM. GP3269 exhibits anticonvulsant activity in rats[1].
CAS Number
186393-42-0
UNSPSC
12352005
Target
Adenosine Kinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gp3269.html
Solubility
10 mM in DMSO
Smiles
O[C@H]([C@@H]([C@H](O1)C)O)[C@]1([H])N2C3=NC=NC(NC4=CC=C(C=C4)F)=C3C(C5=CC=CC=C5)=C2
Molecular Formula
C23H21FN4O3
Molecular Weight
420.44
References & Citations
[1]Mark D. ErionGensia, et al. Design, Synthesis and Anticonvulsant Activity of the Potent Adenosine Kinase Inhibitor GP3269.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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