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KP1019

CAT: 0804-HY-19118Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19118Size:1 Each
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Description
KP1019 (FFC14A) is a Ru (III) -based anti-metastatic and cytotoxic anti-cancer agent. KP1019 induces DNA damage and apoptosis in cancer cells[1][2].
CAS Number
124875-20-3
Product Name Alternative
FFC14A
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kp1019.html
Solubility
10 mM in DMSO
Smiles
[Cl-][Ru+3]([Cl-])([Cl-])([N]1=CC2=C(N1)C=CC=C2)([N]3=CC4=C(N3)C=CC=C4)[Cl-].C5(C=NN6)=C6C=CC=C5.[H+]
Molecular Formula
C21H19Cl4N6Ru
Molecular Weight
598.30
References & Citations
[1]Shannon K Stevens, et al. The anticancer ruthenium complex KP1019 induces DNA damage, leading to cell cycle delay and cell death in Saccharomyces cerevisiae. Mol Pharmacol. 2013 Jan;83 (1) :225-34.|[2]Gemma K Gransbury, et al. Comparison of KP1019 and NAMI-A in tumour-mimetic environments. Metallomics. 2016 Aug 1;8 (8) :762-73.|[3]A Bergamo, et al. Inhibitory Effects of the Ruthenium Complex KP1019 in Models of Mammary Cancer Cell Migration and Invasion. Met Based Drugs. 2009;2009:681270.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
ZEA87520-01KP1019

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