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VER-00158411

CAT: 0804-HY-18942Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-18942Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VER-00158411 is a checkpoint kinase 1 (CHK1) and CHK2 inhibitor with IC50 values of 4.4 nM and 4.5 nM, respectively[1].
CAS Number
1174664-88-0
UNSPSC
12352005
Target
Checkpoint Kinase (Chk)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ver-00158411.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN(CC2=CC=CC=C2)N=C1)NC(C=C3C(N4)=CC5=C4C=CC(OCC(C)(C)CN(C)C)=C5)=CNC3=O
Molecular Formula
C31H34N6O3
Molecular Weight
538.64
References & Citations
[1] Ann Gee Lisa OOI, et al. Combination therapy. 26 July 2018. WO2018136010A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Chk1; Chk2

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