Bremelanotide

• Description:

  Bremelanotide (PT-141) is an analogue of α-melanocyte-stimulating hormone (α-MSH) . Bremelanotide activates the mPOA and other hypothalamic and limbic regions of the brain involved in sexual behavior. Bremelanotide can be used for researching hypoactive sexual desire disorders[1].

• Product Name Alternative:

  PT-141

• UNSPSC:

  12352209

• Hazard Statement:

  H302, H312, H332

• Target:

  Melanocortin Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/bremelanotide.html

• Purity:

  99.69

• Solubility:

  H2O : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(N[C@](CCCCNC(C[C@@H]1NC([C@@H](NC(C)=O)CCCC)=O)=O)([H])C(O)=O)[C@@H](NC([C@@H](NC([C@@](NC([C@@H](NC1=O)CC2=CN=CN2)=O)([H])CC3=CC=CC=C3)=O)CCCNC(N)=N)=O)CC4=CNC5=CC=CC=C45

• Molecular Formula:

  C50H68N14O10

• Molecular Weight:

  1025.16

• Precautions:

  H302, H312, H332

• References & Citations:

  [1]Pfaus J, et al. Bremelanotide: an overview of preclinical CNS effects on female sexual function. J Sex Med. 2007 Nov;4 Suppl 4:269-79.|[2]Molinoff PB, et al. PT-141: a melanocortin agonist for the treatment of sexual dysfunction. Ann N Y Acad Sci. 2003 Jun;994:96-102.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Peptides

• Clinical Information:

  Launched

• CAS Number:

  [189691-06-3]