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Berberine-d6 (chloride)

CAT: 0804-HY-18258SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-18258SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Berberine-d6 (chloride) is the deuterium labeled Berberine chloride. Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties[1].
Product Name Alternative
Natural Yellow 18-d6 (chloride)
UNSPSC
12352005
Target
Antibiotic; Autophagy; Bacterial; Endogenous Metabolite; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS) ; Topoisomerase
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])([2H])OC1=C(OC([2H])([2H])[2H])C2=C[N+]3=C(C4=CC5=C(C=C4CC3)OCO5)C=C2C=C1.[Cl-]
Molecular Formula
C20H12D6ClNO4
Molecular Weight
377.85
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Cai Y, et al. Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo. J Nat Med. 2014 Jan;68 (1) :53-62.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported