Azithromycin-d3

CAT: 0804-HY-17506S-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-17506S-01Size:1 mg
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Description
Azithromycin-d3 is the deuterium labeled Azithromycin. Azithromycin (CP-62993) is a macrolide antibiotic useful for the treatment of a number of bacterial infections[1][2].
CAS Number
[163921-65-1]
UNSPSC
12352005
Target
Antibiotic; Autophagy; Bacterial; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Autophagy; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Purity
99.7
Solubility
DMSO : ≥100 mg/mL (ultrasonic; warming) |Ethanol : ≥ 100mg/mL
Smiles
C[C@H]([C@@H](O[C@@]([H])([C@@H]1O)O[C@@H](C[C@@H]1N(C)C)C)[C@](C[C@@H](C)CN2C([2H])([2H])[2H])(C)O)[C@H](O[C@@]([H])(C[C@]3(OC)C)O[C@H]([C@@H]3O)C)[C@@H](C)C(O[C@@H]([C@@](O)([C@@H]([C@H]2C)O)C)CC)=O
Molecular Formula
C38H69D3N2O12
Molecular Weight
752.00
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Menzel M, et al. Azithromycin augments rhinovirus-induced IFNβ via cytosolic MDA5 in experimental models of asthma exacerbation. Oncotarget. 2017 Mar 18.|[3]Vandooren J, et al. Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study. PLoS One. 2017 Apr 3;12 (4) :e0174853.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
Macrolide

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