Azithromycin-d3

• Description :

  Azithromycin-d3 is the deuterium labeled Azithromycin. Azithromycin (CP-62993) is a macrolide antibiotic useful for the treatment of a number of bacterial infections[1][2].

• UNSPSC :

  12352005

• Target :

  Antibiotic; Autophagy; Bacterial; Isotope-Labeled Compounds

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Anti-infection; Autophagy; Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection; Cancer

• Purity :

  99.7

• Solubility :

  DMSO : ≥100 mg/mL (ultrasonic; warming) |Ethanol : ≥ 100mg/mL

• Smiles :

  C[C@H]([C@@H](O[C@@]([H])([C@@H]1O)O[C@@H](C[C@@H]1N(C)C)C)[C@](C[C@@H](C)CN2C([2H])([2H])[2H])(C)O)[C@H](O[C@@]([H])(C[C@]3(OC)C)O[C@H]([C@@H]3O)C)[C@@H](C)C(O[C@@H]([C@@](O)([C@@H]([C@H]2C)O)C)CC)=O

• Molecular Formula :

  C38H69D3N2O12

• Molecular Weight :

  752.00

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Menzel M, et al. Azithromycin augments rhinovirus-induced IFNβ via cytosolic MDA5 in experimental models of asthma exacerbation. Oncotarget. 2017 Mar 18.|[3]Vandooren J, et al. Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study. PLoS One. 2017 Apr 3;12 (4) :e0174853.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• Isoform :

  Macrolide

• CAS Number :

  [163921-65-1]