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Acebutolol

CAT: 0804-HY-17497-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-17497-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Acebutolol is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol is used for hypertension, angina pectoris and cardiac arrhythmias research[1][2][3].
CAS Number
37517-30-9
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/acebutolol.html
Purity
99.72
Solubility
10 mM in DMSO
Smiles
CCCC(NC1=CC=C(OCC(O)CNC(C)C)C(C(C)=O)=C1)=O
Molecular Formula
C18H28N2O4
Molecular Weight
336.43
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Piquette-Miller, M. and F. Jamali, Pharmacokinetics and multiple peaking of acebutolol enantiomers in rats. Biopharm Drug Dispos, 1997. 18 (6) : p. 543-56.|[2]Bristow MR, et al. Treatment of chronic heart failure with β-adrenergic receptor antagonists: a convergence of receptor pharmacology and clinical cardiology. Circ Res. 2011 Oct 28;109 (10) :1176-94.|[3]Mostafavi, S., R. Lewanczuk, and R. Foster, Influence of acebutolol and metoprolol on cardiac output and regional blood flow in rats. Biopharm Drug Dispos, 2000. 21 (4) : p. 121-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor

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