Tripelennamine

CAT: 0804-HY-17428ASize: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-17428ASize:1 Each

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Description

Tripelennamine, an ethylenediamine derivative, is a potent histamine H1-receptor antagonist. Tripelennamine lessens the allergic response of the organism caused by histamine. Tripelennamine can be used for the research of rhinitis, conjunctivitis, and allergic and anaphylactic reactions[1][2][3].

CAS Number

91-81-6

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Endogenous Metabolite; Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tripelennamine.html

Solubility

10 mM in DMSO

Smiles

CN(C)CCN(CC1=CC=CC=C1)C2=NC=CC=C2

Molecular Formula

C16H21N3

Molecular Weight

255.36

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Manohar M, et al. H1-receptor antagonist, tripelennamine, does not affect arterial hypoxemia in exercising Thoroughbreds. J Appl Physiol. 2002 Apr;92 (4) :1515-23.|[2]Wasfi IA, et al. Comparative disposition of tripelennamine in horses and camels after intravenous administration. J Vet Pharmacol Ther. 2000 Jun;23 (3) :145-52.|[3]Yeh SY, et al. The pharmacokinetics of pentazocine and tripelennamine. Clin Pharmacol Ther. 1986 Jun;39 (6) :669-76.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

H1 Receptor

Alternative Products

Catalog	Name
T60392-01	Tripelennamine
T1269-01	Tripelennamine hydrochloride
C09155-50mg	Tripelennamine HCl
MBS5805349	Tripelennamine citrate

Tripelennamine

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