Caspofungin

• Description:

  Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β- (l,3) -D-glucan[1][2].

• Product Name Alternative:

  MK-0991; L-743872

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H312, H332

• Target:

  Antibiotic; Bacterial; Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/caspofungin.html

• Purity:

  99.74

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@](NC([C@](NC([C@@](C[C@H]1O)([H])N(C1)C2=O)=O)([H])[C@H](O)[C@H](C(C=C3)=CC=C3O)O)=O)([H])[C@H](O)CCN)N(CC[C@@H]4O)[C@]4([H])C(N[C@@H]([C@@H](C[C@@H](C(N[C@@]2([H])[C@H](O)C)=O)NC(CCCCCCCC[C@@H](C)C[C@@H](C)CC)=O)O)NCCN)=O

• Molecular Formula:

  C52H88N10O15

• Molecular Weight:

  1093.31

• Precautions:

  H302, H312, H332

• References & Citations:

  [1]Flattery AM, et, al. Efficacy of caspofungin in a juvenile mouse model of central nervous system candidiasis. Antimicrob Agents Chemother. 2011 Jul;55 (7) :3491-7. |[2]Mojumder DK, et, al. Evaluating retinal toxicity of intravitreal caspofungin in the mouse eye. Invest Ophthalmol Vis Sci. 2010 Nov;51 (11) :5796-803.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• CAS Number:

  [162808-62-0]