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Radalbuvir

CAT: 0804-HY-16750Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-16750Size:1 Each
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Description
Radalbuvir (GS-9669) is a non-nucleoside inhibitor of nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp) . Radalbuvir shows strong anti-HCV potency (GT1a intrinsic EC50 = 2.9 nM, GT1b EC50 = 6 nM) [1].
CAS Number
1314795-11-3
Product Name Alternative
GS-9669
UNSPSC
12352005
Target
HCV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/radalbuvir.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H]1CCC(C)=CC1)N([C@H]2CC[C@@](CO[C@H]3CCOC3)(O)CC2)C(C=C(C#CC(C)(C)C)S4)=C4C(O)=O
Molecular Formula
C30H41NO6S
Molecular Weight
543.71
References & Citations
[1]Zhou Z, et al. Small molecule NS5B RdRp non-nucleoside inhibitors for the treatment of HCV infection: A medicinal chemistry perspective. Eur J Med Chem. 2022 Jul 8;240:114595.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
T34254-01Radalbuvir

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