Tigapotide

• Description :

  Tigapotide (PCK-3145) is an anti-tumour peptide that reduces the development of skeletal metastases associated with prostate cancer. Tigapotide induces apoptosis and reduces tumour parathyroid hormone-related peptide (PTHrP) levels[1].

• Product Name Alternative :

  PCK-3145

• UNSPSC :

  12352209

• Target :

  Apoptosis

• Type :

  Peptides

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/tigapotide.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CCC(O)=O)C(N[C@H](C(O)=O)[C@H](O)C)=O)=O)NC([C@H](CSCNC(C)=O)NC([C@H]([C@H](O)C)NC([C@H](CSCNC(C)=O)NC([C@H]([C@H](O)C)NC([C@H](CCC(O)=O)NC([C@H](CSCNC(C)=O)NC([C@H](CC(N)=O)NC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CCC(N)=O)NC([C@@H](NC([C@@H](N)CCC(O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C82H119N21O34S3

• Molecular Weight :

  2039.14

• References & Citations :

  [1]Pippa N, et al. Advanced nanocarriers for an antitumor peptide. Journal of nanoparticle research, 2013, 15 (11) : 1-13.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  Phase 1

• CAS Number :

  [848084-83-3]