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Ozarelix

CAT: 0804-HY-16375Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-16375Size:1 Each
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Description
Ozarelix (D-63153) is a GnRH antagonist. Ozarelix induces cell apoptosis and arrests cell in G2/M phase. Ozarelix can be used in the research of prostate cancer[1].
CAS Number
295350-45-7
Product Name Alternative
D-63153
UNSPSC
12352209
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis; GnRH Receptor
Type
Peptides
Related Pathways
Apoptosis; GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ozarelix.html
Solubility
10 mM in DMSO
Smiles
OC(C=C1)=CC=C1C[C@H](N(C)C([C@H](CO)NC([C@H](NC([C@H](NC([C@H](NC(C)=O)CC2=CC3=C(C=CC=C3)C=C2)=O)CC4=CC=C(C=C4)Cl)=O)CC5=CN=CC=C5)=O)=O)C(N[C@H](CCCCNC(N)=O)C(N[C@@H](CCCC)C(N[C@@H](CCCNC(N)=N)C(N6[C@@H](CCC6)C(N[C@H](C)C(N)=O)=O)=O)=O)=O)=O
Molecular Formula
C72H96ClN17O14
Molecular Weight
1459.09
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Festuccia C, et al. Ozarelix, a fourth generation GnRH antagonist, induces apoptosis in hormone refractory androgen receptor negative prostate cancer cells modulating expression and activity of death receptors. Prostate. 2010 Sep 1;70 (12) :1340-9.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
Phase 2

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