TAMRA-isoADPr

• UNSPSC Description :

  TAMRA-isoADPr is a fluorescently tagged iso-ADP-ribose tracer compound. TAMRA-isoADPr is a high-affinity tracer for the RNF146 WWE domain with a Kd of 45.2 nM[1].

• Target Antigen :

  Fluorescent Dye

• Type :

  Dye Reagents

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/tamra-isoadpr.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CN(C)C1=CC(OC(C=C(N(C)C)C=C2)=C2C34OC(C5=CC(C(NCCCCCCNC(CCC6=CN([C@H]7[C@@H](O[C@@H]8[C@H](O)[C@H](O)[C@@H](COP(O)(O)=O)O8)[C@H](N9C=NC%10=C9N=CN=C%10N)O[C@@H]7COP(O)(O)=O)N=N6)=O)=O)=CC=C54)=O)=C3C=C1

• Molecular Weight :

  1193.06

• References & Citations :

  [1]Kewen Peng, et al. Iso-ADP-Ribose Fluorescence Polarization Probe for the Screening of RNF146 WWE Domain Inhibitors. ACS Chem Biol. 2024 Jan 18.

• Shipping Conditions :

  Room temperature

• Clinical Information :

  No Development Reported