MR-2088

• UNSPSC Description:

  MR-2088 is a selective ULK1/ULK2 inhibitor with pEC50 values of 8.3 and 8.7, respectively. MR-2088 selectively inhibits autophagy through ULK1/2 mediated inhibition[1].

• Target Antigen:

  Autophagy; ULK

• Type:

  Reference compound

• Related Pathways:

  Autophagy

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mr-2088.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NCC(F)(F)F)C1=CC(C2=CN=C3C(C=C(C4=CCCNC4)N3)=C2)=CS1

• Molecular Weight:

  406.42

• References & Citations:

  [1]Alisa Morozova, et al. Development of potent and selective ULK1/2 inhibitors based on 7-azaindole scaffold with favorable in vivo properties. European Journal of Medicinal Chemistry. 29 December 2023, 116101.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2922531-69-7