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MR-2088

CAT: 0804-HY-162100Size: 1 EachDry Ice: NoHazardous: No
CAT#: HY-162100Size: 1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MR-2088 is a selective ULK1/ULK2 inhibitor with pEC50 values of 8.3 and 8.7, respectively. MR-2088 selectively inhibits autophagy through ULK1/2 mediated inhibition[1].
CAS Number
[2922531-69-7]
UNSPSC
12352005
Target
Autophagy; ULK
Type
Reference compound
Related Pathways
Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mr-2088.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC(F)(F)F)C1=CC(C2=CN=C3C(C=C(C4=CCCNC4)N3)=C2)=CS1
Molecular Formula
C19H17F3N4OS
Molecular Weight
406.42
References & Citations
[1]Alisa Morozova, et al. Development of potent and selective ULK1/2 inhibitors based on 7-azaindole scaffold with favorable in vivo properties. European Journal of Medicinal Chemistry. 29 December 2023, 116101.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ULK1; ULK2

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