Echothiopate iodide

• Description :

  Echothiopate iodide is a potent hBChE (human butyrylcholinesterase) inhibitor. Echothiopate iodide is a long-acting anticholinesterase agent. Echothiopate iodide can be used for glaucoma research[1][2].

• Product Name Alternative :

  Echothiophate iodide

• UNSPSC :

  12352211

• Hazard Statement :

  H300-H311+H331-H400

• Target :

  Cholinesterase (ChE)

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/echothiopate-iodide.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=P(SCC[N+](C)(C)C)(OCC)OCC.[I-]

• Molecular Formula :

  C9H23INO3PS

• Molecular Weight :

  383.23

• Precautions :

  P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P361+P364-P391-P403+P233-P405-P501

• References & Citations :

  [1]Nachon F, et al. Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging. Biochemistry. 2005 Feb 1;44 (4) :1154-62.|[2]HUMPHREYS JA, et al. Systemic effects produced by echothiophate iodide in treatment of glaucoma. Arch Ophthalmol. 1963 Jun;69:737-43.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• Isoform :

  BChE

• CAS Number :

  [513-10-0]