Lenalidomide 4'-PEG2-azide

• Description:

  Lenalidomide 4'-PEG2-azide is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide 4'-PEG2-azide can be connected to the ligand for protein by a linker to form PROTAC[1].

• UNSPSC:

  12352005

• Target:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/lenalidomide-4-peg2-azide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [N-]=[N+]=NCCOCCOCCNC1=CC=CC2=C1CN (C3C (NC (CC3) =O) =O) C2=O

• Molecular Formula:

  C19H24N6O5

• Molecular Weight:

  416.43

• References & Citations:

  [1]Liu H, et al. Construction of an IMiD-based azide library as a kit for PROTAC research. Org Biomol Chem. 2021 Jan 6;19 (1) :166-170.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2399455-48-0