Lenalidomide 4'-PEG2-azide

CAT: 0804-HY-161134-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0804-HY-161134-01Size:10 mg
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Description
Lenalidomide 4'-PEG2-azide is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide 4'-PEG2-azide can be connected to the ligand for protein by a linker to form PROTAC[1].
CAS Number
[2399455-48-0]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lenalidomide-4-peg2-azide.html
Solubility
10 mM in DMSO
Smiles
[N-]=[N+]=NCCOCCOCCNC1=CC=CC2=C1CN(C3C(NC(CC3)=O)=O)C2=O
Molecular Formula
C19H24N6O5
Molecular Weight
416.43
References & Citations
[1]Liu H, et al. Construction of an IMiD-based azide library as a kit for PROTAC research. Org Biomol Chem. 2021 Jan 6;19 (1) :166-170.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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