T18.3 aptamer (sodium)
CAT:
804-HY-160067
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

T18.3 aptamer (sodium)
- UNSPSC Description: T18.3 aptamer sodium is an anticoagulant RNA aptamer targeting FV/Va and eliminates the interaction of FV/FVa with phospholipid membranes. T18.3 aptamer sodium exhibits clinically relevant anticoagulant activity in plasma and whole blood and acts synergistically with low molecular weight heparin. The anticoagulant activity of T18.3 aptamer sodium is effectively and rapidly reversed by protamine sulfate[1].
- Target Antigen: Others
- Type: Oligonucleotides
- Related Pathways: Others
- Applications: COVID-19-immunoregulation
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/t18-3-aptamer-sodium.html
- Solubility: 10 mM in DMSO
- Smiles: [T18.3 aptamer (sodium)]
- References & Citations: [1]Soule EE, Yu H, Olson L, Naqvi I, Kumar S, Krishnaswamy S, Sullenger BA. Generation of an anticoagulant aptamer that targets factor V/Va and disrupts the FVa-membrane interaction in normal and COVID-19 patient samples. Cell Chem Biol. 2022 Feb 17;29(2):215-225.e5.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported