T18.3 aptamer (sodium)

CAT:

804-HY-160067

Size:

Inquire

Price:

Ask

For price, please contact [email protected]

UNSPSC Description: T18.3 aptamer sodium is an anticoagulant RNA aptamer targeting FV/Va and eliminates the interaction of FV/FVa with phospholipid membranes. T18.3 aptamer sodium exhibits clinically relevant anticoagulant activity in plasma and whole blood and acts synergistically with low molecular weight heparin. The anticoagulant activity of T18.3 aptamer sodium is effectively and rapidly reversed by protamine sulfate[1].
Target Antigen: Others
Type: Oligonucleotides
Related Pathways: Others
Applications: COVID-19-immunoregulation
Field of Research: Infection
Assay Protocol: https://www.medchemexpress.com/t18-3-aptamer-sodium.html
Solubility: 10 mM in DMSO
Smiles: [T18.3 aptamer (sodium)]
References & Citations: [1]Soule EE, Yu H, Olson L, Naqvi I, Kumar S, Krishnaswamy S, Sullenger BA. Generation of an anticoagulant aptamer that targets factor V/Va and disrupts the FVa-membrane interaction in normal and COVID-19 patient samples. Cell Chem Biol. 2022 Feb 17;29(2):215-225.e5.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
CTApt-024	Anti-PSMA Aptamer Aptamer
AR-317-U	synthetic CD4 aptamer, RNA aptamer
CTApt-163	Anti-Vaspin binding aptamer Aptamer
CTApt-151	Anti-RBP4 binding aptamer Aptamer
AR-319-U	Anti-EGFR Aptamer, RNA aptamer
AD-132-U	PC12 Cells (Aptamer, unlabeled17a) , DNA Aptamer
AD-133-U	PCB106 (Aptamer, unlabeled 9.3) , DNA Aptamer
AR-288-U	CD4 (Aptamer, unlabeled 7), RNA Aptamer
AR-238-U	Heteroaryldihydropyrimidine (Aptamer, unlabeled 21), RNA Aptamer
AD-134-U	PCB72 (Aptamer, unlabeled 9.3) , DNA Aptamer