S2.2 aptamer (sodium)

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804-HY-160062

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UNSPSC Description: S2.2 aptamer sodium is a nucleic acid aptamer targeting the mucin MUC1 and can be used for targeted imaging of MCF-7 cancer cells. S2.2 aptamer sodium was labeled with Cy5, and when fluorescent silicon nanodots (SiND) were present, the fluorescence was quenched; when MUC1 was also present, the fluorescence was restored. S2.2 aptamer sodium detects MUC1 with a linear range of 3.33-250 nM[1].
Target Antigen: Mucin
Type: Oligonucleotides
Related Pathways: Immunology/Inflammation
Applications: Cancer-programmed cell death
Field of Research: cancer
Assay Protocol: https://www.medchemexpress.com/s2-2-aptamer-sodium.html
Solubility: 10 mM in DMSO
Smiles: [S2.2 aptamer (sodium)]
References & Citations: [1]Zhang Y, Guo S, Huang H, Mao G, Ji X, He Z. Silicon nanodot-based aptasensor for fluorescence turn-on detection of mucin 1 and targeted cancer cell imaging. Anal Chim Acta. 2018 Dec 4;1035:154-160.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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