S2.2 aptamer (sodium)

• UNSPSC Description:

  S2.2 aptamer sodium is a nucleic acid aptamer targeting the mucin MUC1 and can be used for targeted imaging of MCF-7 cancer cells. S2.2 aptamer sodium was labeled with Cy5, and when fluorescent silicon nanodots (SiND) were present, the fluorescence was quenched; when MUC1 was also present, the fluorescence was restored. S2.2 aptamer sodium detects MUC1 with a linear range of 3.33-250 nM[1].

• Target Antigen:

  Mucin

• Type:

  Oligonucleotides

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/s2-2-aptamer-sodium.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [S2.2 aptamer (sodium)]

• References & Citations:

  [1]Zhang Y, Guo S, Huang H, Mao G, Ji X, He Z. Silicon nanodot-based aptasensor for fluorescence turn-on detection of mucin 1 and targeted cancer cell imaging. Anal Chim Acta. 2018 Dec 4;1035:154-160.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported