P12FR2 aptamer (sodium)

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804-HY-160061

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UNSPSC Description: P12FR2 aptamer sodium is a 2'-fluoropyrimidine-modified RNA aptamer targeting human PAUF with an estimated apparent KD of 77 nM. P12FR2 aptamer sodium inhibits PAUF-induced migration of PANC-1 (human pancreatic cancer cells) in wound healing assays and suppresses tumor growth in a mouse CFPAC-1 pancreatic cancer model[1].
Target Antigen: Biochemical Assay Reagents
Type: Oligonucleotides
Related Pathways: Others
Applications: Cancer-programmed cell death
Field of Research: cancer
Assay Protocol: https://www.medchemexpress.com/p12fr2-aptamer-sodium.html
Solubility: 10 mM in DMSO
Smiles: [P12FR2 aptamer (sodium)]
References & Citations: [1]Kim YH, Sung HJ, Kim S, Kim EO, Lee JW, Moon JY, Choi K, Jung JE, Lee Y, Koh SS, Rhee SG, Heo K, Kim IH. An RNA aptamer that specifically binds pancreatic adenocarcinoma up-regulated factor inhibits migration and growth of pancreatic cancer cells. Cancer Lett. 2011 Dec 26;313(1):76-83.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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