Products for Research Use Only
RegisterLogin

ET516

CAT: 0804-HY-160020-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-160020-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ET516 is a potent inhibitor of Androgen Receptor. ET516 significantly inhibits the proliferation and tumor growth of prostate cancer cells expressing AR-resistant mutants[1].
CAS Number
2820120-95-2
UNSPSC
12352005
Target
Androgen Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/et516.html
Purity
99.13
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
N#CC1=CC(C(C)(C)C2=CC=C(C=C2)C#CC3=CN=C(NS(=O)(C)=O)N=C3)=CC(Cl)=C1OCCCl
Molecular Formula
C25H22Cl2N4O3S
Molecular Weight
529.44
References & Citations
[1]Xie J, et al. Targeting androgen receptor phase separation to overcome antiandrogen resistance. Nat Chem Biol. 2022 Dec;18 (12) :1341-1350.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
T86384-01ET516

Popular Products