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KDRLKZ-2

CAT: 0804-HY-157559Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157559Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KDRLKZ-2 is a selective E3 ligase. KDRLKZ-2 is a ligand for KLHDC2, with an IC50 value of 0.068 μM in the alphaLISA experiment[1].
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/kdrlkz-2.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CN1C=C(N2C(C(C(C)CC)=CC3=C2CN(C(OCCOC)=O)CC3)=O)C=CC1=O
Molecular Formula
C23H29N3O7
Molecular Weight
459.49
References & Citations
[1]Hickey CM, et al. Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat Struct Mol Biol. 2024 Jan 4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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