DA5-HTL

CAT: 0804-HY-157497Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-157497Size:1 Each
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Description
DA5-HTL is a compound combined dasatinib with HaloTag system efficiently inhibits the growth of the cancer cells with GI50 of 1.923 nM[1].
UNSPSC
12352005
Target
Apoptosis; Autophagy; Bcr-Abl; Src
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/da5-htl.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C(Cl)=CC=C1)NC(C2=CN=C(S2)NC3=CC(N4CCN(CC4)CCOC(NCCOCCOCCOCCOCCOCCCCCCCl)=O)=NC(C)=N3)=O
Molecular Formula
C39H58Cl2N8O8S
Molecular Weight
869.90
References & Citations
[1]Kwak C, et al. Identification of proteomic landscape of drug-binding proteins in live cells by proximity-dependent target ID. Cell Chem Biol. 2022 Dec 15;29 (12) :1739-1753.e6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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