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RO7075573

CAT: 0804-HY-157492Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157492Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RO7075573 (compound 3) is an antibiotics that targets the lipopolysaccharide (LPS) transport machine in Acinetobacter. RO7075573 protects mice from A. baumannii infections[1][2].
CAS Number
2097284-11-0
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ro7075573.html
Solubility
10 mM in DMSO
Smiles
CN(C([C@@H](NC([C@@H]1CCCN)=O)CCCCN)=O)[C@H](C(NCC(C(SC2=NC=CC=C2CN1)=C3Cl)=C(C=C3)Cl)=O)CC4=CNC5=CC=CC=C45
Molecular Formula
C36H44Cl2N8O3S
Molecular Weight
739.76
References & Citations
[1]Pahil KS, et al. A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature. 2024 Jan 3.|[2]Zampaloni C, et al. A novel antibiotic class targeting the lipopolysaccharide transporter. Nature. 2024 Jan;625 (7995) :566-571.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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