PPO-IN-6

• Description :

  PPO-IN-6 is a protoporphyrinogen oxidase (PPO) inhibitor that blocks the production of heme and chlorophyll. Pop-in-6 can be used IN the detection and research of cancer and other diseases[1].

• CAS Number :

  [125727-57-3]

• UNSPSC :

  12352005

• Target :

  Protoporphyrinogen IX oxidase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ppo-in-6.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C2=C(C(N1C3=C(F)C=C(OCC(N4CC#C)=O)C4=C3)=O)C=CC=C2

• Molecular Formula :

  C19H11FN2O4

• Molecular Weight :

  350.30

• References & Citations :

  [1]Zhang L, et al. Bioactive conformation analysis of cyclic imides as protoporphyrinogen oxidase inhibitor by combining DFT calculations, QSAR and molecular dynamic simulations. Bioorg Med Chem. 2009 Jul 15;17 (14) :4935-42.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported