RegisterLogin

Dobutamine

CAT: 0804-HY-15746A-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-15746A-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Dobutamine is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors) . Dobutamine is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine can increase cardiac output and correct hypoperfusion[1][2][3][4].
CAS Number
[34368-04-2]
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/dobutamine.html
Concentration
10mM
Purity
98.75
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(CCNC(C)CCC2=CC=C(O)C=C2)C=C1O
Molecular Formula
C18H23NO3
Molecular Weight
301.38
Precautions
H302, H312, H332
References & Citations
[1]Tuttle RR, et al. Dobutamine: development of a new catecholamine to selectively increase cardiac contractility. Circ Res. 1975 Jan;36 (1) :185-96.|[2]Vallet B, et al. Dobutamine: mechanisms of action and use in acute cardiovascular pathology. Ann Cardiol Angeiol (Paris) . 1991 Jun;40 (6) :397-402.|[3]Tyrankiewicz U , et al. Characterization of the cardiac response to a low and high dose of dobutamine in the mouse model of dilated cardiomyopathy by MRI in vivo. J Magn Reson Imaging. 2013 Mar;37 (3) :669-77.|[4]Tibayan FA, et al. Dobutamine increases alveolar liquid clearance in ventilated rats by beta-2 receptor stimulation. Am J Respir Crit Care Med. 1997 Aug;156 (2 Pt 1) :438-44.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
α adrenergic receptor; β adrenergic receptor
Citation 01
Biochem Pharmacol. 2025 Nov 29:244:117576.|Comput Struct Biotechnol J. 2023 Jul 7:21:3490-3502.|Environ Toxicol. 2024 Mar;39 (3) :1682-1699.|Anal Chem. 2025 Jul 15;97 (27) :14220-14229.|Front Cell Dev Biol. 2022 Apr 20;10:889656.

Related Products

CatalogName

Alternative Products

CatalogName
T60677-01Dobutamine
M21586-01Dobutamine (hydrochloride)
MBS5786136Dobutamine tartrate
T8149-01Dobutamine hydrochloride
RM-D150200-01Dobutamine Hcl
T31560-01Dobutamine lactobionate
RM-D151643-01Dobutamine Impurity 43
RM-D152689-01Dobutamine Impurity 57
RM-D152701-01Dobutamine Impurity 68
RM-D151686-01Dobutamine Impurity 54

Popular Products