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Z21090

CAT: 0804-HY-157457Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157457Size:1 Each
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Description
Z21090 (ZL40) is a potent inhibitor of PDE4 with the IC50 value of 37.4 nM and oral bioavailability. Z21090 plays an important role in alcohol-related diseases research[1].
CAS Number
2992690-71-6
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/z21090.html
Solubility
10 mM in DMSO
Smiles
CCOC1=NC(Cl)=CC2=C1C=NN2CCCC(O)=O
Molecular Formula
C12H14ClN3O3
Molecular Weight
283.71
References & Citations
[1]Lei Zheng, et al. Discovery of 4-Ethoxy-6-chloro-5-azaindazoles as Novel PDE4 Inhibitors for the Treatment of Alcohol Use Disorder and Alcoholic Liver Diseases. J Med Chem. 2023 Dec 29.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE4

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CatalogName
GTR19234591-01Z21090

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