(8S)-Methyl zearalenone

(8S)-Methyl zearalenone

• CAS Number: 1137720-39-8
• UNSPSC Description: (8S)-Methyl zearalenone (ZEA analogue 5) is a selective CBR1 (carbonyl reductase 1) inhibitor, with an IC50 of 0.21 μM[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/8s-methyl-zearalenone.html
• Solubility: 10 mM in DMSO
• Smiles: OC1=C2C(/C=C/CC[C@H](C)C(CCC[C@@H](OC2=O)C)=O)=CC(O)=C1
• Molecular Weight: 332.39
• References & Citations: [1]Tobias J Zimmermann, et al. Discovery of a potent and selective inhibitor for human carbonyl reductase 1 from propionate scanning applied to the macrolide zearalenone. Bioorg Med Chem. 2009 Jan 15;17(2):530-6.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported