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IPRMT1

CAT: 0804-HY-157151Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157151Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IPRMT1 is a potent and selective PRMT1 inhibitor for breast cancer research. iPRMT1 inhibits breast cancer cell growth in vitro and in vivo with EC50 values of 90, 70, and 9 nM in MCF7, T47D, and MDA-MB-231 cells, respectively[1].
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/iprmt1.html
Solubility
10 mM in DMSO
Smiles
OC(CC1)CCN1C(C=C2)=CC=C2NC3=NC(N4[C@H]5CC6=CC=CC=C46)=C(C=N3)NC5=O
Molecular Formula
C24H24N6O2
Molecular Weight
428.49
References & Citations
[1]Li WJ, et al. Targeting PRMT1-mediated SRSF1 methylation to suppress oncogenic exon inclusion events and breast tumorigenesis. Cell Rep. 2023 Nov 7;42 (11) :113385.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T208320-01IPRMT1

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