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Y08262

CAT: 0804-HY-157134Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157134Size:1 Each
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Description
Y08262 is a potent and selective CBP bromodomain inhibitor. Y08262 selectively inhibits the CBP bromodomain with an IC50 value of 73.1 nM. Y08262 can be used for the research of acute myeloid leukemia (AML) [1].
CAS Number
2450965-18-9
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/y08262.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C2C=C(OC)C=CN2C(C(C)=O)=C1)NC3=CC=CC(C4=CN(C5CC5)N=C4)=C3F
Molecular Formula
C24H21FN4O3
Molecular Weight
432.45
References & Citations
[1]Xiang Q, et al. Discovery of a potent and selective CBP bromodomain inhibitor (Y08262) for treating acute myeloid leukemia. Bioorg Chem. 2023 Oct 30;142:106950.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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