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UniPR1449

CAT: 0804-HY-157020Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157020Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UniPR1449 is an antagonist of EphA2 receptor, with th KD of 3.8±2.4 μM, that plays an important role in cancer[1].
UNSPSC
12352005
Target
Ephrin Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/unipr1449.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=CC=C1)(N2C3=C(C(C[C@H](NC(CC[C@H]([C@@H](CCC4C(CC=C(C5)[C@@]6(CC[C@@H]5O)C)C6CC7)[C@]47C)C)=O)CC(O)=O)=C2)C=CC=C3)=O
Molecular Formula
C42H54N2O6S
Molecular Weight
714.95
References & Citations
[1]Lorenzo Guidetti. Et al. Molecular Determinants of EphA2 and EphB2 Antagonism Enable the Design of Ligands with Improved Selectivity. J Chem Inf Model. 2023 Nov 1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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