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ITH15004

CAT: 0804-HY-156986-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-156986-01Size:1 mg
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Description
ITH15004 is a CNS-penetrated P2X7 antagonist, used for the study of neurodegenerative diseases[1].
CAS Number
2600675-12-3
UNSPSC
12352005
Target
P2X Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ith15004.html
Solubility
10 mM in DMSO
Smiles
O=C(CN1C=NC2=C1N=CN=C2Cl)C3=CC=C(C=C3Cl)Cl
Molecular Formula
C13H7Cl3N4O
Molecular Weight
341.58
References & Citations
[1]Francesco Calzaferri, et al. Synthesis and Pharmacological Evaluation of Novel Non-nucleotide Purine Derivatives as P2X7 Antagonists for the Treatment of Neuroinflammation. J Med Chem. 2021 Feb 25;64 (4) :2272-2290.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
464027ITH15004

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