Products for Research Use Only
RegisterLogin

NSC309401

CAT: 0804-HY-156859ASize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-156859ASize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NSC309401 is an inhibitor of E. coli DHFR (IC50: 189 nM, KD: 14.57 nM) [1].
CAS Number
750522-61-3
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nsc309401.html
Solubility
10 mM in DMSO
Smiles
NC(C=C1)=CC=C1CN2C=CC3=C4C(N=C(N)N=C4N)=CC=C32
Molecular Formula
C17H16N6
Molecular Weight
304.35
References & Citations
[1]Srinivasan B, et al. Insights into the slow-onset tight-binding inhibition of Escherichia coli dihydrofolate reductase: detailed mechanistic characterization of pyrrolo [3,2-f] quinazoline-1,3-diamine and its derivatives as novel tight-binding inhibitors. FEBS J. 2015 May;282 (10) :1922-38.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
MBS5821571NSC309401
MBS5823291NSC309401 dihydrochloride

Popular Products