Products for Research Use Only
RegisterLogin

Nevadistinel

CAT: 0804-HY-156626Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-156626Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Nevadistinel (NYX-458; NYX-3054) is a positive allosteric modulator of N-methyl-D-aspartate (NMDA) receptor. Nevadistinel can be used to inhibit cognitive impairment associated with neurodegenerative diseases, such as mild cognitive impairment, mild Alzheimer's disease, Parkinson's disease, Lewy body disease[1].
CAS Number
2181816-92-0
Product Name Alternative
NYX-458; NYX-3054
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nevadistinel.html
Solubility
10 mM in DMSO
Smiles
O=C1[C@@]2(CC(NCC2)=O)CN1CC3=CC=C(C=C3)OC
Molecular Formula
C15H18N2O3
Molecular Weight
274.32
References & Citations
[1]Khan, et al. Preparation of spiro-lactam as NMDA receptor modulators for the treatment of depression and related disorders. World Intellectual Property Organization, WO2018026798 A1. 2018-02-08.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
MBS5821514Nevadistinel

Popular Products