SETD7-IN-1

CAT: 0804-HY-156455Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-156455Size:1 Each
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Description
SETD7-IN-1 (compound 7) is a PFI-2 (HY-18627) analogue. SETD7-IN-1 is a substrate and inhibitor of histone lysine methyltransferase SETD7, with an IC50 of 0.96 ± 0.10 µM[1].
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/setd7-in-1.html
Solubility
10 mM in DMSO
Smiles
FC1=CC(S(=O)(N[C@H](CC2=CC=CC=C2)C(NCCO)=O)=O)=CC3=C1CNCC3
Molecular Formula
C20H24FN3O4S
Molecular Weight
421.49
References & Citations
[1]Porzberg M, et al. (R) -PFI-2 Analogues as Substrates and Inhibitors of Histone Lysine Methyltransferase SETD7. ChemMedChem. 2023 Oct 23:e202300457.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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