SETD7-IN-1

• Description :

  SETD7-IN-1 (compound 7) is a PFI-2 (HY-18627) analogue. SETD7-IN-1 is a substrate and inhibitor of histone lysine methyltransferase SETD7, with an IC50 of 0.96 ± 0.10 µM[1].

• UNSPSC :

  12352005

• Target :

  Histone Methyltransferase

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/setd7-in-1.html

• Solubility :

  10 mM in DMSO

• Smiles :

  FC1=CC(S(=O)(N[C@H](CC2=CC=CC=C2)C(NCCO)=O)=O)=CC3=C1CNCC3

• Molecular Formula :

  C20H24FN3O4S

• Molecular Weight :

  421.49

• References & Citations :

  [1]Porzberg M, et al. (R) -PFI-2 Analogues as Substrates and Inhibitors of Histone Lysine Methyltransferase SETD7. ChemMedChem. 2023 Oct 23:e202300457.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported