Cabotegravir-d5

CAT: 0804-HY-15592S1Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-15592S1Size:1 mg
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Description
Cabotegravir-d5 is deuterium labeled Cabotegravir.
CAS Number
[2750534-77-9]
Product Name Alternative
GSK-1265744-d5; S/GSK1265744-d5
UNSPSC
12352005
Target
HIV; HIV Integrase; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others
Applications
COVID-19-anti-virus
Field of Research
Infection
Purity
99.31
Solubility
10 mM in DMSO
Smiles
FC1=C(CNC(C2=CN3C(C(N([C@@H](C([2H])([2H])[2H])C([2H])([2H])O4)[C@@]4([H])C3)=O)=C(O)C2=O)=O)C=CC(F)=C1
Molecular Formula
C19H12D5F2N3O5
Molecular Weight
410.38
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Bowers GD, Disposition and metabolism of cabotegravir: a comparison of biotransformation and excretion between different species and routes of administration in humans. Xenobiotica. 2015 Jul 1:1-16.|[3]Reese MJ, Drug interaction profile of the HIV integrase inhibitor cabotegravir: assessment from in vitro studies and a clinical investigation with midazolam. Xenobiotica. 2015 Sep 4:1-12.|[4]Reese MJ, et al. Drug interaction profile of the HIV integrase inhibitor cabotegravir: assessment from in vitro studies and a clinical investigation with midazolam. Xenobiotica. 2015 Sep 4:1-12.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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