DMPE-PEG5000 (ammonium)

• Description:

  DMPE-PEG5000 ammonium (14:0 PEG5000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

• Product Name Alternative:

  14:0 PEG5000 PE (ammonium) ; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy (polyethylene glycol) -5000] (ammonium)

• UNSPSC:

  12352200

• Target:

  Liposome

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/14-0-peg5000-pe.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (NCCOP (O) (OC[C@@H] (COC (CCCCCCCCCCCCC) =O) OC (CCCCCCCCCCCCC) =O) =O) OCCOC.N.[n]

• Molecular Formula:

  (C2H4O) nC35H68NO10P.NH3

• Molecular Weight:

  5000 (Average)

• References & Citations:

  [1]Kandel PK, et al. Incorporating functionalized polyethylene glycol lipids into reprecipitated conjugated polymer nanoparticles for bioconjugation and targeted labeling of cells. Nanoscale. 2011 Mar;3 (3) :1037-45.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Biochemical Assay Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  474922-82-2