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M-PEG-NHS ester (MW 3400)

CAT: 0804-HY-155909Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155909Size:1 Each
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Description
M-PEG-NHS ester (MW 3400) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
CAS Number
92451-01-9
Product Name Alternative
MPEG-SC (MW 3400) ; mPEG-Succinimidyl ester (MW 3400)
UNSPSC
12352200
Hazard Statement
H302-H315-H319
Target
Biochemical Assay Reagents
Type
Biochemical Assay Reagents
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/m-peg-nhs-ester-mw-3400.html
Solubility
10 mM in DMSO
Smiles
COCCOCC(ON1C(CCC1=O)=O)=O.[n]
Molecular Formula
(C2H4O) nC7H9NO5
Molecular Weight
3400 (Average)
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Jin M, et al. Preparation of pegylated lumbrokinase and an evaluation of its thrombolytic activity both in vitro and in vivo[J]. Acta Pharmaceutica Sinica B, 2013, 3 (2) : 123-129.
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

Chemical Information

(2,5-Dioxopyrrolidin-1-yl) 2-(2-hydroxyethoxy)acetate;2-methoxyethanol
CAS Number92451-01-9
PubChem CID71312614
IUPAC Name(2,5-dioxopyrrolidin-1-yl) 2-(2-hydroxyethoxy)acetate;2-methoxyethanol
Molecular FormulaC11H19NO8
Molecular Weight293.27
Topological Polar Surface Area123
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Heavy Atom Count20
Formal Charge0
Complexity275
SMILES
COCCO.C1CC(=O)N(C1=O)OC(=O)COCCO
InChI
InChI=1S/C8H11NO6.C3H8O2/c10-3-4-14-5-8(13)15-9-6(11)1-2-7(9)12;1-5-3-2-4/h10H,1-5H2;4H,2-3H2,1H3
InChIKey
NYXRHTOXAYVBMV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of (2,5-Dioxopyrrolidin-1-yl) 2-(2-hydroxyethoxy)acetate;2-methoxyethanol
CAS: 92451-01-9
CID: 71312614
Formula: C11H19NO8
MW: 293.27
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight293.27
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Exact Mass293.11106656
Monoisotopic Mass293.11106656
Topological Polar Surface Area123 Ų
Heavy Atom Count20
Formal Charge0
Complexity275
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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