RegisterLogin

IV-275

CAT: 0804-HY-155889Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-155889Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
IV-275 is an inhibitor of both BRG1 and BRM bromodomains. IV-275 increases the extent of DNA damage induced by Temozolomide (HY-17364) and Bleomycin (HY-108345) . IV-275 inhibits the invasiveness of GBM cells. IV-275 enhances Temozolomide-induced cell death and the apoptosis-inducing activity of Temozolomide[1].
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/iv-275.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(N2[C@H]3CN([C@@H](C2)C3)C(OC4=CC(F)=C(C=C4)F)=O)C=C1
Molecular Formula
C19H18F2N2O3
Molecular Weight
360.35
References & Citations
[1]Yang C, et al. Next-generation bromodomain inhibitors of the SWI/SNF complex enhance DNA damage and cell death in glioblastoma. J Cell Mol Med. 2023 Sep;27 (18) :2770-2781.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-160505-01RO-275
HY-P1206-01CH 275
HY-119131AK 275
HY-173417Antibacterial agent 275
HY-174392Anticancer agent 275
HY-W952925CRBN ligand-275
HY-P2516-01Tau Peptide (275-305) (Repeat 2 domain)
HY-N6945-01Mogroside IV
HY-N6014Asperosaponin IV
HY-D0932Sudan IV

Alternative Products

CatalogName
T79642-01IV-275
A8171-SEntinostat (MS-275,SNDX-275)
1590-1MS-275 (Entinostat, SNDX-275)
M30709-01CH 275
MBS808119-01MS 275
MBS577477BML-275
T125783-01Crucigasterin 275
abx076834-01MS-275
MBS5774749AK 275
BUP21185-01RO-275

Popular Products