5-fluoro-dCTP

• Description :

  5-fluoro-dCTP is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase[1].

• Product Name Alternative :

  5-Fluoro-2′-deoxycytidine 5′-triphosphate

• UNSPSC :

  12352005

• Target :

  DNA/RNA Synthesis

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/5-fluoro-dctp.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O[C@H]1C[C@H](N2C=C(F)C(N)=NC2=O)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O

• Molecular Formula :

  C9H15FN3O13P3

• Molecular Weight :

  485.15

• References & Citations :

  [1]Olszewska A, et al. Cleavage of DNA containing 5-fluorocytosine or 5-fluorouracil by type II restriction endonucleases. Bioorg Med Chem. 2015 Nov 1;23 (21) :6885-90.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [79671-09-3]