5-fluoro-dCTP

• UNSPSC Description:

  5-fluoro-dCTP is a fluorinated pyrimidine dNTP that can be used as a substrate for the incorporation of fluorine modification into specific DNA sequences by primer extension (PEX) catalyzed by Pwo polymerase[1].

• Target Antigen:

  DNA/RNA Synthesis

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/5-fluoro-dctp.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1C[C@H](N2C=C(F)C(N)=NC2=O)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O

• Molecular Weight:

  485.15

• References & Citations:

  [1]Olszewska A, et al. Cleavage of DNA containing 5-fluorocytosine or 5-fluorouracil by type II restriction endonucleases. Bioorg Med Chem. 2015 Nov 1;23(21):6885-90.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  79671-09-3