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Mz438

CAT: 0804-HY-155698Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155698Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mz438 is high-affinity and selective fluorescent CXCR2 ligand. Mz438 is a small-molecule-based fluorescent probe targeting the IABS of CXCR2[1].
UNSPSC
12171500
Target
CXCR; Fluorescent Dye
Type
Dye Reagents
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/mz438.html
Solubility
10 mM in DMSO
Smiles
CC(C)([C@H](C1=CC=C(O1)C)NC2=C(C(C2=O)=O)NC(C=CC=C3C(NCC(N=N4)=CN4CCOCCOCCOCCNC(C5=CC=C(C([O-])=O)C(C(C(C=C6)=C(O7)C=C6N(C)C)=C8C7=C/C(C=C8)=[N+](C)/C)=C5)=O)=O)=C3O)C
Molecular Formula
C57H63N9O12
Molecular Weight
1066.16
References & Citations
[1]Huber ME, et, al. Fluorescent Ligands Enable Target Engagement Studies for the Intracellular Allosteric Binding Site of the Chemokine Receptor CXCR2. J Med Chem. 2023 Jul 27;66 (14) :9916-9933.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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CatalogName
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