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KSK94

CAT: 0804-HY-155616-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-155616-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KSK94 is a high-affinity histamine H3 receptor antagonist, with Kis of 7.9, 2958, 75.2 nM for H3 receptor, sigma-1, sigma-2 receptor respectively. KSK94 can be used for research of nociceptive and neuropathic pain[1].
CAS Number
2566716-07-0
UNSPSC
12352005
Target
Histamine Receptor; Sigma Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ksk94.html
Solubility
10 mM in DMSO
Smiles
N#CC(C=C1)=CC=C1C2=CC=C(OCCCN3CCN(C4=CC=NC=C4)CC3)C=C2
Molecular Formula
C25H26N4O
Molecular Weight
398.50
References & Citations
[1]Szczepańska K, et al. Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain. J Med Chem. 2023 Jul 27;66 (14) :9658-9683.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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