CB2 receptor antagonist 3

• UNSPSC Description:

  CB2 receptor antagonist 3 (compound (S)-1) is an inverse agonist of the cannabinoid receptor CB2R with Kd=39 nM. CB2 receptor antagonist 3 can be used as a tool to synthesize a variety of CB2R probes[1].

• Target Antigen:

  Cannabinoid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/cb2-receptor-antagonist-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C1=CC(OC)=C([C@@]2([H])C=C(CN)[C@@H]3C(C)(C)[C@H]2C3)C(OC)=C1)(C)[C@@H](CCCCCN=[N+]=[N-])C4=CC=CC=C4

• Molecular Weight:

  530.74

• References & Citations:

  [1]Carreira E et al. Flipping the GPCR Switch: Structure–Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists[J]. 2023.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported