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HSK205

CAT: 0804-HY-155341-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-155341-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HSK205 is a dual FLT3 and haspin inhibitor, with IC50 of 0.187 nM for FLT3. HSK205 has antitumor activity[1].
CAS Number
3022263-37-9
UNSPSC
12352005
Target
FLT3; Haspin Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hsk205.html
Purity
98.01
Solubility
DMSO : 4.17 mg/mL (ultrasonic)
Smiles
O=C(NCC1=NC(C)=CN1)C(C=C2)=CC=C2C(C3=C4CCCC3)=NC5=C4C(C=NN6)=C6C=C5
Molecular Formula
C26H24N6O
Molecular Weight
436.51
References & Citations
[1]Allison L Kempen, et al. Dual FLT3/haspin kinase inhibitor based on 3 H-pyrazolo[4,3- f]quinoline scaffold with activities against acute myeloid leukemia. RSC Med Chem. 2023 Jul 14;14 (9) :1743-1754.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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