MRS7925

CAT: 0804-HY-155117Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-155117Size:1 Each
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Description
MRS7925 (Compound 43) is a 5-HT2BR antagonist (Ki: 17 nM) . MRS7925 can be used for research of fibrosis[1].
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mrs7925.html
Solubility
10 mM in DMSO
Smiles
OC[C@]12[C@@H](O)[C@@H](O)[C@H](N3C(N=C(I)N=C4N[C@H](C5CC5)C6CCC6)=C4N=C3)[C@H]1C2
Molecular Formula
C20H26IN5O3
Molecular Weight
511.36
References & Citations
[1]Tosh DK, et al. Structure activity relationships of 5-HT2B and 5-HT2C serotonin receptor antagonists: N6, C2 and 5'-Modified (N) -methanocarba-adenosine derivatives. Eur J Med Chem. 2023 Nov 5;259:115691.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor

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