mTOR inhibitor-12

• UNSPSC Description:

  mTOR inhibitor-12 (Compound 11) is a selective brain penetrant mTOR inhibitor without genotoxicity risk. mTOR inhibitor-12 can be used for the research of CNS diseases[1].

• Target Antigen:

  mTOR

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/mtor-inhibitor-12.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@H]1COCCN1C2=C3N=C(C4=CSC=N4)NC3=NC(N5[C@@H](C)COCC5)=C2

• Molecular Weight:

  400.50

• References & Citations:

  [1]Bonazzi S,et al. Identification of Brain-Penetrant ATP-Competitive mTOR Inhibitors for CNS Syndromes. J Med Chem. 2023 Jul 13;66(13):9095-9119.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3033409-34-3