3’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-3’-fluorouridine

3’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-3’-fluorouridine

• CAS Number: 129015-60-7
• UNSPSC Description: 3’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-3’-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/3-deoxy-5-o-4-4-dimethoxytrityl-3-fluorouridine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@@H]1[C@H](F)[C@@H](COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)O[C@H]1N5C(NC(C=C5)=O)=O
• Molecular Weight: 548.56
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported