2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine

2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine

• CAS Number: 690271-27-3
• UNSPSC Description: 2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1]. 2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-3-di-o-isopropylidene-4-alpha-c-azidouridine.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC1=O)C=CN1[C@H](O2)[C@H]3[C@H](OC(C)(C)O3)[C@]2(CO)N=[N+]=[N-]
• Molecular Weight: 325.28
• References & Citations: [1]Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported