Methyl 4-C-hydroxymethyl-2,3-O-isopropylidene-beta-D-ribofuranoside

• UNSPSC Description:

  Methyl 4-C-hydroxymethyl-2,3-O-isopropylidene-beta-D-ribofuranoside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/methyl-4-c-hydroxymethyl-2-3-o-isopropylidene-beta-d-ribofuranoside.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OCC1(CO)O[C@@H](OC)[C@H]2[C@@H]1OC(C)(C)O2

• Molecular Weight:

  234.25

• References & Citations:

  [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  55797-67-6