Methyl 4-C-hydroxymethyl-2,3-O-isopropylidene-beta-D-ribofuranoside

Methyl 4-C-hydroxymethyl-2,3-O-isopropylidene-beta-D-ribofuranoside

• CAS Number: 55797-67-6
• UNSPSC Description: Methyl 4-C-hydroxymethyl-2,3-O-isopropylidene-beta-D-ribofuranoside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/methyl-4-c-hydroxymethyl-2-3-o-isopropylidene-beta-d-ribofuranoside.html
• Solubility: 10 mM in DMSO
• Smiles: OCC1(CO)O[C@@H](OC)[C@H]2[C@@H]1OC(C)(C)O2
• Molecular Weight: 234.25
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported